The multiple pathways of endocannabinoid metabolism: a zoom out.
نویسندگان
چکیده
Abbreviations. – AA, Arachidonic acid; AEA, arachidonoylethanolamide (anandamide); 2-AG, 2arachidonoylglycerol; CNS, central nervous system; COX, cyclooxygenase; CRC, colorectal carcinoma cells; DMP, discovery metabolite profiling; ERK, extracellular-signal-regulated kinase; FAAH, fatty acid amide hydrolase; HCA-7, human colon adenocarcinoma; 11-HETE-G, 11-hydroxyeicosatetraenoic acid glycerol ester; 15-HETE-G, 15-hydroxyeicosatetraenoic acid glycerol ester; HFF, human foreskin fibroblasts; HHT, 12-hydroxyheptadecatrienoic acid; HIV, human immunodeficiency virus; HPLC/MS, high-pressure liquid chromatography coupled to mass-spectrometric analysis; HPETE, hydroperoxyeicosatetraenoic acid; HPETEA, hydroxyperoxyeicosa-5,8,12,14-tetraenoylethanolamide; HPETE-G, hydroxyperoxyeicosa-5,8,10,14-tetraenoic acid glycerol ester; IFN-g, interferon-g ; i.v., intravenous; LOX, lipoxygenase; LPS, lipopolysaccharide; MAGL, monoacylglycerol lipase; MAGLcy, cytosolic monoacylglycerol lipase; MAGLm, membrane-bound enzyme responsible for monoacylglycerol hydrolysis; mIPSCs, miniature inhibitory postsynaptic currents; MS, mass spectrometry; NAAA, Nacylethanolamine-hydrolyzing acid amidase; NADA, N-arachidonoyldopamine; NPAA, N-palmitoylethanolamine-hydrolyzing acid amidase; OEA, oleoylethanolamide; 2-OG, 2-oleoylglycerol; PC, phosphorylcholine; PEA, palmitoylethanolamide; PGD2-G, prostaglandin D2 glycerol ester; PGE2EA, prostaglandin E2 ethanolamide; PGE2-G, prostaglandin E2 glycerol ester; PGG2, endoperoxidecontaining prostaglandin G2; PGH2, endoperoxide-containing prostaglandin H2; PGH2-G, prostaglandin H2 glycerol ester; PGI, prostacyclin; PGIS, prostacyclin synthase; PPAR-a, peroxisome proliferatoractivated receptor-alpha; PPAR-g, peroxisome proliferator-activated receptor-gamma; RBL, rat basophilic leukemia; THC, tetrahydrocannabinol; TRPV-1, transient receptor potential vanilloid; TXA, thromboxane; TXAS, thromboxane synthase; URB597, cyclohexylcarbamic acid 3’-carbamoyl biphenyl-3-yl ester.
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ورودعنوان ژورنال:
- Chemistry & biodiversity
دوره 4 8 شماره
صفحات -
تاریخ انتشار 2007